Journal Article

FZJ-2021-05920

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles

Jablonski, M. ; Poghossian, A. ; Severins, R. ; Keusgen, M. ; Wege, C. ; Schöning, M. J. (Corresponding author)FZJ*

2021
MDPI Basel

This record in other databases:    

Please use a persistent id in citations: http://hdl.handle.net/2128/33188  doi:10.3390/mi12010057

Abstract: Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta2O5-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta2O5-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles.

---

Contributing Institute(s):

1. Bioelektronik (IBI-3)

Research Program(s):

1. 5244 - Information Processing in Neuronal Networks (POF4-524) (POF4-524)

Appears in the scientific report 2022

---

Database coverage:
; ; ; ; Article Processing Charges ; Clarivate Analytics Master Journal List ; Current Contents - Engineering, Computing and Technology ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF < 5 ; JCR ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---