Journal Article

FZJ-2022-05712

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Different facets of object-use pantomime: online TMS evidence on the role of the supramarginal gyrus

Kleineberg, N. (Corresponding author)FZJ* ; Tscherpel, C. ; Fink, G. R.FZJ* ; Grefkes, C.FZJ* ; Weiss, P. H.FZJ*

2022
Elsevier New York, NY

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Please use a persistent id in citations: http://hdl.handle.net/2128/33065  doi:10.1016/j.cortex.2022.06.018

Abstract: BackgroundA key question in apraxia research is which specific cognitive processes in pantomiming the parietal cortex supports. The manipulation-based hypothesis and the technical-reasoning hypothesis ascribe different roles to the inferior parietal lobule (IPL).ObjectiveWe elucidated the role of the left supramarginal gyrus (SMG, i.e., part of IPL) during the processing of different aspects of object-use pantomime.MethodsThirty-one healthy participants matched pantomimes with the corresponding object (PO) or the corresponding situation (PS) during online transcranial magnetic stimulation (TMS) interference applied to left SMG, compared to a control stimulation (vertex). Notably, the object corresponding to a given pantomime was explicitly not shown in the PS task, excluding the possibility to analyse a physical object. Matching an object to the corresponding situation (OS) served as a control task.ResultsTMS interference with left SMG significantly affected response times for both investigated pantomime tasks (PO and PS); the effect in the PO task significantly correlated with that in the PS task. As expected, no TMS effect was observed in the control task (OS).ConclusionLeft SMG does not only establish a link between pantomime and a manipulable object but is also involved in pantomime recognition and comprehension. That TMS interfered with both pantomime tasks supports the manipulation-based hypothesis, assuming that the IPL recruits stored gesture engrams whenever pantomimes are processed.

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 5251 - Multilevel Brain Organization and Variability (POF4-525) (POF4-525)
2. 5252 - Brain Dysfunction and Plasticity (POF4-525) (POF4-525)

Appears in the scientific report 2022

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Database coverage:
; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Current Contents - Social and Behavioral Sciences ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Social Sciences Citation Index ; Web of Science Core Collection

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