Open Access

The development of magnetic resonance imaging (MRI) based biomarkers is a constant endeavorin the field of clinical neuroscience. Although these biomarkers hold great potential, only few havebeen adopted for routine clinical use. [...]

We study the frustration pattern of a square lattice with in situ fabricated Nb-Pt-Nb four-terminal Josephson junctions. The four-terminal geometry gives rise to a checkerboard pattern of alternating fluxes f, f' piercing the plaquettes, which stabilizes the Berezinskii-Kosterlitz-Thouless transition even at irrational flux quanta per plaquette, due to an unequal repartition of integer flux sum f + f' into alternating plaquettes. [...]

Today, 13 intra-amyloid-β (Aβ) amyloid precursor protein (APP) gene mutations are known to cause familial Alzheimer’s disease (AD). Most of them are point mutations causing an increased production or a change in the conformation of Aβ. [...]

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