Buchbeitrag

Adaptive algebraic multigrid methods have meanwhile established themselves as standardsolvers in lattice QCD computations on current supercomputers. In this paper we review re-cent additions and recent new use cases for the solvers, in particular our DD-αAMG methodand report performance results obtained on JUWELS at JSC..

When solving linear systems with the overlap operator at nonzero chemical potential $μ$ in lattice QCD one needs, at every iteration of the iterative solver, to apply the sign function evaluated on a non-Hermitian operator $Q_μ$ times a vector, i.e., $sign(Q_μ)v$. In this work we describe how deflation and (the more recently proposed) polynomial preconditioning can be applied to this problem, in particular in the context of lattice QCD. [...]

race estimation is a significant challenge in lattice QCD simulations. The Hutchinson method's accuracy scales with the square root of the sample size, resulting in high computational costs for precise estimates. [...]

Cell tracking is a key computational task in live-cell microscopy, but fully automated analysis of high-throughput imaging requires reliable and, thus, uncertainty-aware data analysis tools, as the amount of data recorded within a single experiment exceeds what humans are able to overlook. We here propose and benchmark various methods to reason about and quantify uncertainty in linear assignment-based cell tracking algorithms. [...]

Climate change is among the most critical challenges confronting society today, primarily driven by the enormous amount of CO2 emissions into the atmosphere, with chemical industries being a major source. The increasing demand for petrochemical products further worsens this problem. [...]

Optogenetic Control of B. subtilis Gene Expression using the CcaSR System -- The Yeast Optogenetic Toolkit (yOTK) for Spatiotemporal Control of gene Expression in Budding Yeast -- Optoribogenetic Modulation of Transcription -- A Red Light-Activatable Endogenous Gene Transcription System with Red-CPTS -- Targeted Activation of Programmed Cell Death Pathways by Optogenetics -- Modulating Optogenetic YAP In Vitro and In Vivo -- Design and Use of AsLOV2-Based Optogenetic Tools for Actin Imaging -- Optogenetic Engineered Living Materials -- Light-Controlled Secretion and Injection of Proteins into Eukaryotic Cells by Optogenetic Control of the Bacterial Type III Secretion System -- Synthesis and Application of Photcaged Isopropyl β-d-1-thiogalactopyranoside for Light-Mediated Control of Bacterial Gene Expression -- Optogenetic Clustering and Stimulation of the T Cell Receptor in Non-Genetically Modified Human T Cells -- Extracellular Optogenetics to Interrogate Unmodified Primary Cell Functions -- Alternating Cellular Functions by Optogenetic Control of Organelles -- Light-Inducible Deformation of Mitochondria in Live Cells -- Chlorophyll-Based Optogenetics to Control Membraneless Organelles -- Automated Plate Reader-Based Assays of Light-Activated GPCRs -- Modular Light-Emitting Diode Shelving Systems for Scalable Optogenetics -- Analysis of Light-Controlled Artificial Cell-Cell Adhesions

Markov Chain Monte Carlo simulations of lattice Quantum Chromodynamics (QCD) are the onlyknown tool to investigate non-perturbatively the theory of the strong interaction and are requiredto perform precision tests of the Standard Model of Particle Physics. As the Markov Chain isa serial process, the sole option for improving the sampling rate is accelerating each individualupdate step. [...]

In the RC$^{\star}$ collaboration, we simulate lattice QCD+QED using $C-$periodic spatial boundary conditions to ensure that locality, gauge invariance, and translational invariance are preserved throughout the calculation. We present our progress in computing isospin-breaking (IB) corrections to the leading hadronic contribution to $(g-2)_\mu$. [...]

Full QCD+QED simulations allow to evaluate isospin breaking corrections to hadron masses. With the openQxD code, we are able to perform these simulations employing C-periodic boundary conditions, implemented through a doubling of the physical lattice along one spatial direction.The use of these boundary conditions introduces non-zero Wick contractions between two quark or two antiquark fields, that, in the case of the computation of baryon masses, lead to partially connected additional contributions that we expect to vanish in the infinite volume limit. [...]