Book/Dissertation / PhD Thesis

FZJ-2023-01724

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Morphological and functional characterization of layer 5 neurons in rat medial prefrontal cortex, their synaptic microcircuitry and serotonin modulation

Rama, R. (Corresponding author)FZJ*

2023
Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag Jülich
ISBN: 978-3-95806-688-5

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Please use a persistent id in citations: urn:nbn:de:0001-20230718093345772-5225649-6  doi:10.34734/FZJ-2023-01724

Abstract: Medial prefrontal cortex (Cortex praefrontalis medialis, mPFC) is a part of the association cortex that serves to process and integrate synaptic inputs from sensory and motor cortical areas. The mPFC plays important roles in numerous cognitive processes, such as emotional processing, executive function, decision making, spatial orientation, long-term memory and impulse control. Compared to other cortical areas, the mPFC has a particularly high density of serotonergic axons which originate from the dorsal and medial raphe nuclei; they play a crucial role in regulating the development and function of the neocortex. For this reason, a basic knowledge of the role of serotonin (5-HT) and its receptors (5-HTRs) function in the mPFC in modulating cortical activity is crucial.

Note: Dissertation, RWTH Aachen University, 2022

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Contributing Institute(s):

1. Jara-Institut Brain structure-function relationships (INM-10)

Research Program(s):

1. 899 - ohne Topic (POF4-899) (POF4-899)

Appears in the scientific report 2023

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Database coverage:
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