Journal Article

FZJ-2024-06762

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Context-dependency of the REM sleep behavior disorder screening questionnaire - Clinical utility under scrutiny

Röttgen, S. (Corresponding author)FZJ* ; Doppler, C. E. J.FZJ* ; Seger, A. ; Kalbe, E. ; Fink, G. R.FZJ* ; Sommerauer, M.FZJ* ; Ophey, A.

2025
Elsevier Science Amsterdam [u.a.]

This record in other databases:    

Please use a persistent id in citations: doi:10.1016/j.parkreldis.2024.107211  doi:10.34734/FZJ-2024-06762

Abstract: AbstractIntroduction: The REM Sleep Behavior Disorder (RBD) Screening Questionnaire (RBDSQ) is a widely established screening tool for detecting isolated RBD (iRBD). However, its accuracy may depend on its application context, e.g., the individuals' awareness of their RBD status. The present work aims to describe the context-dependency and retest reliability of the RBDSQ in an iRBD cohort setting.Methods: Ninety-four individuals with video-polysomnography confirmed iRBD answered the RBDSQ during pre-polysomnography screening (V0) and post-diagnosis (V1).Results: The RBDSQ total score significantly differed between V0 and V1 (F(1,92) = 8.02, p = .006, ηp2 = 0.019). The intraclass correlation coefficient (ICC2,1) of the RBDSQ showed moderate reliability between consecutive timepoints (V0-V1ICC2,1 = 0.544). The highest Cohen's κ was reached for items 5, 6.3, 6.4, 8, and 9 across timepoint comparisons (0.409 ≤ Cohen's κ ≤ 0.660).Conclusion: Our findings underscore the context-dependency of the RBDSQ and fluctuations in self-awareness of sleep-related behaviors, necessitating a critical appraisal of questionnaire-based RBD screening tools. Future studies should explore strategies to improve the reliability and accuracy of RBD screening tools, considering the dynamic nature of sleep-related behavior.Keywords: Disease awareness; REM sleep behavior disorder; Reliability; Screening questionnaire.

---

Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 5252 - Brain Dysfunction and Plasticity (POF4-525) (POF4-525)
2. DFG project G:(GEPRIS)491111487 - Open-Access-Publikationskosten / 2022 - 2024 / Forschungszentrum Jülich (OAPKFZJ) (491111487) (491111487)

---

Database coverage:
; ; ; Clarivate Analytics Master Journal List ; Current Contents - Clinical Medicine ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---