Journal Article

FZJ-2025-03016

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Asymmetric synthesis of C–N axially chiral carbazoles via axial-to-axial chirality transfer

Myllek, S. ; Lencer, P.FZJ* ; Klischan, M. K. T. ; Henssen, B.FZJ* ; Neudecker, P.FZJ* ; Breugst, M. ; Pietruszka, J. (Corresponding author)FZJ*

2025
Royal Society of Chemistry Cambridge

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Please use a persistent id in citations: doi:10.1039/D5OB00587F  doi:10.34734/FZJ-2025-03016

Abstract: C–N axially chiral carbazole derivatives were synthesised by an intramolecular Buchwald–Hartwig amination starting from C–C axially chiral biaryls utilising an axial-to-axial chirality transfer with enantiospecificities up to 91%. The mechanism of the chirality transfer was investigated via DFT calculations.

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Contributing Institute(s):

1. Strukturbiochemie (IBI-7)
2. Biotechnologie (IBG-1)

Research Program(s):

1. 5241 - Molecular Information Processing in Cellular Systems (POF4-524) (POF4-524)

Appears in the scientific report 2025

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Database coverage:
; ; ; Chemical Reactions ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Current Contents - Physical, Chemical and Earth Sciences ; Essential Science Indicators ; IF < 5 ; Index Chemicus ; JCR ; National-Konsortium ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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