Journal Article FZJ-2014-03439

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Source localization of brain activity using helium free interferometer

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2014
American Institute of Physics Melville, NY

Applied physics letters 104, 213705 () [10.1063/1.4880097]

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Abstract: To detect extremely small magnetic fields generated by the human brain, currently all commercial magnetoencephalography (MEG) systems are equipped with low-temperature (low-Tc) superconducting quantum interference device (SQUID) sensors that use liquid helium for cooling. The limited and increasingly expensive supply of helium, which has seen dramatic price increases recently, has become a real problem for such systems and the situation shows no signs of abating. MEG research in the long run is now endangered. In this study, we report a MEG source localization utilizing a single, highly sensitive SQUID cooled with liquid nitrogen only. Our findings confirm that localization of neuromagnetic activity is indeed possible using high-Tc SQUIDs. We believe that our findings secure the future of this exquisitely sensitive technique and have major implications for brain research and the developments of cost-effective multi-channel, high-Tc SQUID-based MEG systems.

Classification:

Contributing Institute(s):
  1. Mikrostrukturforschung (PGI-5)
  2. Physik der Medizinischen Bildgebung (INM-4)
  3. JARA-BRAIN (JARA-BRAIN)
Research Program(s):
  1. 423 - Sensorics and bioinspired systems (POF2-423) (POF2-423)

Appears in the scientific report 2014
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Medline ; OpenAccess ; Allianz-Lizenz / DFG ; Current Contents - Social and Behavioral Sciences ; JCR ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection
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Document types > Articles > Journal Article
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Institute Collections > INM > INM-4
Institute Collections > PGI > PGI-5
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 Record created 2014-06-11, last modified 2024-06-10


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