Journal Article

FZJ-2014-04138

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png 18 F-Labelled Intermediates for Radiosynthesis by Modular Build-Up Reactions: Newer Developments

Ermert, J. (Corresponding Author)FZJ*

2014
Hindawi New York [u.a.]

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Please use a persistent id in citations: http://hdl.handle.net/2128/7839  doi:10.1155/2014/812973

Abstract: This brief review gives an overview of newer developments in 18F-chemistry with the focus on small 18F-labelled molecules as intermediates for modular build-up syntheses. The short half-life (<2 h) of the radionuclide requires efficient syntheses of these intermediates considering that multistep syntheses are often time consuming and characterized by a loss of yield in each reaction step. Recent examples of improved synthesis of 18F-labelled intermediates show new possibilities for no-carrier-added ring-fluorinated arenes, novel intermediates for tri[18F]fluoromethylation reactions, and 18F-fluorovinylation methods

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Contributing Institute(s):

1. Nuklearchemie (INM-5)

Research Program(s):

1. 333 - Pathophysiological Mechanisms of Neurological and Psychiatric Diseases (POF2-333) (POF2-333)
2. 89573 - Neuroimaging (POF2-89573) (POF2-89573)

Appears in the scientific report 2014

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Database coverage:
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