Journal Article

FZJ-2015-04290

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Change in electrodermal activity after acute tryptophan depletion associated with aggression in young people with attention deficit hyperactivity disorder (ADHD)

von Polier, G. G. ; Biskup, C. S. ; Kötting, W. F. ; Bubenzer, S. ; Helmbold, K. ; Eisert, A. ; Gaber, T. J. ; Zepf, F. D. (Corresponding Author)FZJ*

2014
Springer Wien [u.a.]

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Please use a persistent id in citations: doi:10.1007/s00702-013-1119-5

Abstract: We investigated the impact of acute tryptophan depletion (ATD) and reduced brain serotonin synthesis on physiological arousal in 15 young people with ADHD participating in an aggression-inducing game. ATD was not associated with altered physiological arousal, as indexed by electrodermal activity (EDA). Baseline aggression was negatively correlated with the mean ATD effect on EDA. In accordance with the low arousal theory related to aggressive behavior, subjects with reduced physiological responsiveness/lower electrodermal reactivity to ATD tended to display elevated externalizing behavior.

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Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)

Research Program(s):

1. 333 - Pathophysiological Mechanisms of Neurological and Psychiatric Diseases (POF2-333) (POF2-333)

Appears in the scientific report 2015

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Database coverage:
; BIOSIS Previews ; Current Contents - Life Sciences ; IF < 5 ; JCR ; NCBI Molecular Biology Database ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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