Journal Article FZJ-2016-01660

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Mikrobiologische Einzelzell-Phänotypencharakterisierung im Mikrochip

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2016
Spektrum Heidelberg

Biospektrum 22(1), 48 - 50 () [10.1007/s12268-016-0658-3]

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Abstract: Microbes adapt to environmental changes by DNA embedded mechanisms (e. g. resistance) or non-DNA based phenotypical differentiation (e. g. tolerance). Single-cell fluorescence imaging combined with environmental control by microfluidic devices helps to unravel phenotypical changes of single microbial cells in isogenic cell populations. Therefore, the intracellular implementation of fluorescent molecules by genetic modification or dynamic staining is essential for non-invasive live-cell imaging.

Classification:

Contributing Institute(s):
  1. Biotechnologie (IBG-1)
Research Program(s):
  1. 581 - Biotechnology (POF3-581) (POF3-581)

Appears in the scientific report 2016
Database coverage:
NCBI Molecular Biology Database ; No Authors Fulltext ; SCOPUS
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Dokumenttypen > Aufsätze > Zeitschriftenaufsätze
Institutssammlungen > IBG > IBG-1
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