Journal Article

PreJuSER-31378

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Towards a capacitive enzyme sensor for direct determination of organophosphorus pesticides: Fundamentals studies and aspects of development

Schöning, M. J.FZJ* ; Arzdorf, M.FZJ* ; Mulchandani, E. J. M. ; Chen, W. ; Mulchandani, A.

2003
MDPI Basel

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Please use a persistent id in citations: http://hdl.handle.net/2128/21028  doi:10.3390/s30600119

Abstract: The realisation of a miniaturised potentiometric enzyme biosensor is presented. The biosensor chip utilises the enzyme organophosphorus hydrolase (OPH) for the direct determination of pesticides. The transducer structure of the sensor chip consists of a pH-sensitive capacitive electrolyte-insulator-semiconductor (EIS) structure that reacts towards pH changes caused by the OPH-catalysed hydrolysis of the organophosphate compounds. The biosensor is operated versus a conventional Ag/AgCl reference electrode. Measurements were performed in the capacitance/voltage (C/V) and constant capacitance (ConCap) mode for the two different pesticides paraoxon and parathion. For the development of this new type of biosensor, different immobilisation strategies, influence of buffer composition and concentration, transducer material, detection limit, long-term stability and selectivity have been studied.

Keyword(s): J ; capacitive EIS sensor (auto) ; OPH (auto) ; semiconductor technology (auto) ; enzyme biosensor (auto)

Note: Record converted from VDB: 12.11.2012

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Contributing Institute(s):

1. Institut für Bio- und Chemosensoren (ISG-2)

Research Program(s):

1. Materialien, Prozesse und Bauelemente für die Mikro- und Nanoelektronik (I01)

Appears in the scientific report 2003

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Database coverage:

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