Journal Article

FZJ-2018-01578

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Cytoarchitectonic and receptorarchitectonic organization in Broca's region and surrounding cortex

Zilles, K. (Corresponding author)FZJ* ; Amunts, K.FZJ*

2018
Elsevier Amsterdam [u.a.]

This record in other databases:    

Please use a persistent id in citations: http://hdl.handle.net/2128/17977  doi:10.1016/j.cobeha.2018.02.011

Abstract: Broca's region was originally described as a cortical site in the inferior frontal gyrus, where speech impairment occurs after brain lesions. However, this clinico-pathological definition does not define the underlying microstructural correlates. Two cytoarchitectonic areas (BA44, BA45) were identified as correlates of Broca's region in the inferior frontal opercular and triangular parts, respectively. Recent microstructural analyses based on the distribution of transmitter receptors suggest a further segregation of BA44 and BA45 and the inclusion of neighboring areas in the adjacent inferior frontal and precentral sulci as well as in the frontal operculum as structural correlates of Broca's region. Here, we review these recent cytoarchitectonic and receptorarchitectonic findings in Broca's region, and compare them with functional imaging data containing sufficient topographical specifications. Finally, Broca's region of the human brain is compared with the homologue region in the brain of apes, baboon and macaque monkey.

---

Contributing Institute(s):

1. Strukturelle und funktionelle Organisation des Gehirns (INM-1)

Research Program(s):

1. 571 - Connectivity and Activity (POF3-571) (POF3-571)
2. HBP SGA1 - Human Brain Project Specific Grant Agreement 1 (720270) (720270)

Appears in the scientific report 2018

---

Database coverage:
; ; SCOPUS

---