Journal Article

FZJ-2018-01623

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png How to Characterize the Function of a Brain Region

GENON, S. (Corresponding author)FZJ* ; Reid, A. ; Langner, R.FZJ* ; Amunts, K.FZJ* ; Eickhoff, S.FZJ*

2018
Elsevier Science Amsterdam [u.a.]

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Please use a persistent id in citations: http://hdl.handle.net/2128/18268  doi:10.1016/j.tics.2018.01.010

Abstract: Many brain regions have been defined, but a comprehensive formalization of each region's function in relation to human behavior is still lacking. Current knowledge comes from various fields, which have diverse conceptions of 'functions'. We briefly review these fields and outline how the heterogeneity of associations could be harnessed to disclose the computational function of any region. Aggregating activation data from neuroimaging studies allows us to characterize the functional engagement of a region across a range of experimental conditions. Furthermore, large-sample data can disclose covariation between brain region features and ecological behavioral phenotyping. Combining these two approaches opens a new perspective to determine the behavioral associations of a brain region, and hence its function and broader role within large-scale functional networks.

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Contributing Institute(s):

1. Gehirn & Verhalten (INM-7)
2. Strukturelle und funktionelle Organisation des Gehirns (INM-1)

Research Program(s):

1. 571 - Connectivity and Activity (POF3-571) (POF3-571)
2. HBP SGA1 - Human Brain Project Specific Grant Agreement 1 (720270) (720270)

Appears in the scientific report 2018

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Database coverage:
; ; ; Current Contents - Life Sciences ; Current Contents - Social and Behavioral Sciences ; Ebsco Academic Search ; IF >= 15 ; JCR ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Social Sciences Citation Index ; Thomson Reuters Master Journal List ; Web of Science Core Collection

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