Journal Article

FZJ-2019-04811

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Trans-thalamic Pathways: Strong Candidates for Supporting Communication between Functionally Distinct Cortical Areas

Zajzon, B. (Corresponding author)FZJ* ; Morales-Gregorio, A.FZJ*

2019
Soc.69657 Washington, DC

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Please use a persistent id in citations: http://hdl.handle.net/2128/23030  doi:10.1523/JNEUROSCI.0656-19.2019

Abstract: The thalamus was long considered a passive relay of sensory information with little or no active role in higher cognitive functions. However, mounting evidence suggests that thalamic nuclei form complex loops with the cortex and are involved in a myriad of cognitive processes, including attention and working memory (Ward, 2013). Although first-order thalamic nuclei (e.g., lateral geniculate nucleus) play a key role in the transmission of ascending sensory input to the cortex, higher-order nuclei (e.g., pulvinar or mediodorsal nucleus) are believed to be involved in sustaining and modulating communication within and between cortical regions (Guillery, 1995). Understanding the functional role of such nuclei in a mechanistic manner requires, in addition to behavioral experiments, a detailed anatomical and physiological mapping of the thalamocortical circuitry.

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Contributing Institute(s):

1. Computational and Systems Neuroscience (INM-6)
2. Theoretical Neuroscience (IAS-6)
3. Jara-Institut Brain structure-function relationships (INM-10)

Research Program(s):

1. 574 - Theory, modelling and simulation (POF3-574) (POF3-574)
2. 571 - Connectivity and Activity (POF3-571) (POF3-571)
3. W2Morrison - W2/W3 Professorinnen Programm der Helmholtzgemeinschaft (B1175.01.12) (B1175.01.12)
4. HBP SGA2 - Human Brain Project Specific Grant Agreement 2 (785907) (785907)
5. DFG project 347572269 - Heterogenität von Zytoarchitektur, Chemoarchitektur und Konnektivität in einem großskaligen Computermodell der menschlichen Großhirnrinde (347572269) (347572269)

Appears in the scientific report 2019

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Database coverage:
; ; BIOSIS Previews ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; IF >= 5 ; JCR ; NCBI Molecular Biology Database ; PubMed Central ; SCOPUS ; Science Citation Index ; Science Citation Index Expanded ; Web of Science Core Collection

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