Journal Article

FZJ-2021-05888

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png The Voltage Dependent Sidedness of the Reprotonation of the Retinal Schiff Base Determines the Unique Inward Pumping of Xenorhodopsin

Weissbecker, J. ; Boumrifak, C. ; Breyer, M. ; Wießalla, T. ; Shevchenko, V. ; Mager, T. ; Slavov, C. ; Alekseev, A. ; Kovalev, K. ; Gordeliy, V.FZJ* ; Bamberg, E. (Corresponding author) ; Wachtveitl, J. (Corresponding author)

2021
Wiley-VCH Weinheim

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Please use a persistent id in citations: http://hdl.handle.net/2128/29716  doi:10.1002/anie.202103882

Abstract: The unique behaviour of inward proton pumping xenorhodopsins (XeR) makes these microbial rhodopsins an alternative optogenetic tool to the passively transporting light-gated ion channels (e.g. channelrhodopsin-1 and channelrhodopsin-2), because the activation of electrically excitable cells by XeRs is independent from the surrounding physiological conditions. Here, we functionally and spectroscopically characterized XeR from Nanosalina (NsXeR)

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Contributing Institute(s):

1. Strukturbiochemie (IBI-7)

Research Program(s):

1. 5241 - Molecular Information Processing in Cellular Systems (POF4-524) (POF4-524)

Appears in the scientific report 2021

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Database coverage:
; ; ; Chemical Reactions ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Current Contents - Physical, Chemical and Earth Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 10 ; Index Chemicus ; JCR ; Nationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

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