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| Hauptseite > Publikationsdatenbank > Detection of spatio-temporal spike patterns and multiple overlapping cell assemblies during motor behavior |
| Hauptseite > Publikationsdatenbank > Detection of spatio-temporal spike patterns and multiple overlapping cell assemblies during motor behavior |
| Talk (non-conference) (Outreach) | FZJ-2022-06000 |
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2022
Abstract: The cell assembly hypothesis postulates that information processing in the brain entails therepetitive co-activation of groups of neurons [1]. The activation of such assemblies wouldlead to spatio-temporal spike patterns (STPs) at the resolution of a few milliseconds. In orderto test the cell assembly hypothesis, we searched for significant STPs in parallel spike trains,and developed the SPADE method [2,3]. Using SPADE, we analyzed experimental data fromthe motor cortex (M1/PMd) of macaque monkeys (Macaca mulatta) performing areach-to-grasp task [4] and found an abundance of STPs. Quantitative analysis showed thatSTPs are functionally related to behavior, which suggests the presence of assembliesactivated during the task.References:[1] Hebb, D. O. (1949). John Wiley & Sons[2] Stella et al. (2019). Biosystems, 185, 104022. [doi: 10.1016/j.biosystems.2019.104022][3] Stella et al. (2022). eNeuro [doi: 10.1523/ENEURO.0505-21.2022][4] Brochier et al. (2018). Scientific data 5.1: 1-23. [doi: 10.12751/g-node.f83565]
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