Gast ::
| Hauptseite > Publikationsdatenbank > Co-representation of functional brain networks is shaped by cortical myeloarchitecture and reveals individual behavioral ability |
| Hauptseite > Publikationsdatenbank > Co-representation of functional brain networks is shaped by cortical myeloarchitecture and reveals individual behavioral ability |
| Journal Article | FZJ-2024-01503 |
; ; ; ; ; ; ; ; ; ;
2024
Soc.
Washington, DC
This record in other databases: 
Please use a persistent id in citations: doi:10.1523/JNEUROSCI.0856-23.2024 doi:10.34734/FZJ-2024-01503
Abstract: Large-scale functional networks are spatially distributed in the human brain. Despite recent progress in differentiating the functional roles of specific brain networks, how the brain navigates the spatial coordination among them and the biological relevance of this coordination is still not fully understood. Capitalizing on canonical individualized networks derived from functional MRI data, we proposed a new concept, i.e., co-representation of functional brain networks, to delineate the spatial coordination among them. To further quantify the co-representation pattern, we defined two indexes, i.e., the co-representation specificity (CoRS) and intensity (CoRI), for separately measuring the extent of specific and average expression of functional networks at each brain location by using the data from both sexes. We found that the identified pattern of co-representation was anchored by cortical regions with three types of cytoarchitectural classes along a sensory-fugal axis, including, at the first end, primary (idiotypic) regions showing high CoRS, at the second end, heteromodal regions showing low CoRS and high CoRI, at the third end, paralimbic regions showing low CoRI. Importantly, we demonstrated the critical role of myeloarchitecture in sculpting the spatial distribution of co-representation by assessing the association with the myelin-related neuroanatomical and transcriptomic profiles. Furthermore, the significance of manifesting the co-representation was revealed in its prediction of individual behavioral ability. Our findings indicated that the spatial coordination among functional networks was built upon an anatomically configured blueprint to facilitate neural information processing, while advancing our understanding of the topographical organization of the brain by emphasizing the assembly of functional networks.
; 
; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF >= 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
|
The record appears in these collections: |
PDF