Journal Article FZJ-2020-04346

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T1-mapping and dielectric properties evaluation of a 3D printable rubber-elastomeric polymer as tissue mimicking materials for MRI phantoms

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2020
IOP Publ. Bristol

Materials Research Express 7(11), 115306 () [10.1088/2053-1591/abc76f]

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Abstract: In this study, a new series of 3D printable rubber-elastomeric polymer called PORO-LAY materials have been investigated regarding their suitability to serve as tissue mimicking materials (TMMs) for MRI phantoms. PORO-LAY materials have been previously used in biofuel cell developments, particle filtrations and modeling elastic tissues. We evaluated the electrical permittivity, electrical conductivity, spin-lattice T1-relaxation time and acquired the MRI contrast for simple and multi-material complex 3D printed shapes made of PORO-LAY materials at 3.0 T. The results showed a T1 diversity within PORO-LAY materials, which reveals in different MR image contrasts. The outcome favors PORO-LAY as an appropriate candidate that can be used in multi-materials additive manufacturing to produce realistic shapes such as white/grey matter structures for MRI phantoms with visible clear contrast. Finally, this study could serve as a reference and guideline when using these materials as tissue mimicking materials for different types of human body tissues and provide a promising opportunity to design novel phantoms for a wide range of MRI applications.

Keyword(s): Instrument and Method Development (2nd) ; Materials Science (2nd) ; Medicine (2nd)

Classification:

Contributing Institute(s):
  1. Zentralinstitut für Technologie (ZEA-1)
  2. Molekulare Organisation des Gehirns (INM-2)
Research Program(s):
  1. 573 - Neuroimaging (POF3-573) (POF3-573)

Appears in the scientific report 2020
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Medline ; Creative Commons Attribution CC BY 4.0 ; DOAJ ; OpenAccess ; Article Processing Charges ; Clarivate Analytics Master Journal List ; Current Contents - Physical, Chemical and Earth Sciences ; DOAJ Seal ; Essential Science Indicators ; Fees ; IF < 5 ; JCR ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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