Journal Article

FZJ-2020-05084

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Invasive versus non‐invasive mapping of the motor cortex

Weiss Lucas, C. (Corresponding author)Extern* ; Nettekoven, C. ; Neuschmelting, V.Extern* ; Oros‐Peusquens, A. ; Stoffels, G.FZJ* ; Viswanathan, S.FZJ* ; Rehme, A. K. ; Faymonville, A. M. ; Shah, N. J.FZJ* ; Langen, K. J.FZJ* ; Goldbrunner, R. ; Grefkes, C.FZJ*

2020
Wiley-Liss New York, NY

This record in other databases:      

Please use a persistent id in citations: http://hdl.handle.net/2128/26448  doi:10.1002/hbm.25101

Abstract: Precise and comprehensive mapping of somatotopic representations in the motor cortex is clinically essential to achieve maximum resection of brain tumours whilst preserving motor function, especially since the current gold standard, that is, intraoperative direct cortical stimulation (DCS), holds limitations linked to the intraoperative setting such as time constraints or anatomical restrictions. Non‐invasive techniques are increasingly relevant with regard to pre‐operative risk‐assessment. Here, we assessed the congruency of neuronavigated transcranial magnetic stimulation (nTMS) and functional magnetic resonance imaging (fMRI) with DCS. The motor representations of the hand, the foot and the tongue regions of 36 patients with intracranial tumours were mapped pre‐operatively using nTMS and fMRI and by intraoperative DCS. Euclidean distances (ED) between hotspots/centres of gravity and (relative) overlaps of the maps were compared. We found significantly smaller EDs (11.4 ± 8.3 vs. 16.8 ± 7.0 mm) and better spatial overlaps (64 ± 38% vs. 37 ± 37%) between DCS and nTMS compared with DCS and fMRI. In contrast to DCS, fMRI and nTMS mappings were feasible for all regions and patients without complications. In summary, nTMS seems to be the more promising non‐invasive motor cortex mapping technique to approximate the gold standard DCS results.

---

Contributing Institute(s):

1. Kognitive Neurowissenschaften (INM-3)
2. Physik der Medizinischen Bildgebung (INM-4)

Research Program(s):

1. 572 - (Dys-)function and Plasticity (POF3-572) (POF3-572)

Appears in the scientific report 2020

---

Database coverage:
; ; ; BIOSIS Previews ; Biological Abstracts ; Clarivate Analytics Master Journal List ; Current Contents - Life Sciences ; DEAL Wiley ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; Nationallizenz ; PubMed Central ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection

---